A Peer-Reviewed Journal

TABLE OF CONTENTS

VOLUME 1, NUMBER 2 — MAY 2006

CONTENTS

Letter from the Editors 6

Casey Hein Charles M. Cobb

Guest Editorial 8 Grand Rounds with Dr. Brian L. Mealey

Brian L. Mealey

Literature Review 13 Periodontal Disease, Insulin Resistance and

Alan J. Moritz Brian L. Mealey

Diabetes Mellitus: A Review and Clinical Implications

Continuing Education Test 22

Original Article 24 The Impact of Periodontitis on Metabolic

Control and Risk for Diabetic Complications

Maria E. Ryan Oana Carnu Ruth Tenzler

Original Article 36 Combating Diabetes, Obesity, Periodontal Disease and Interrelated Inflammatory Conditions with a Syndemic Approach

Casey Hein Doreen Small

Raising the Bar

Oral Health in Diabetes Care Gaining Traction 48 at the American Diabetes Association:

Casey Hein

Interview with Dr. Nathaniel Clark, Vice President, Clinical Affairs, American Diabetes Association

Tools for Implementation 50

Statement of Editorial Purpose: The editorial purpose of Grand Rounds in Oral-Systemic Medicine^™ is to raise awareness of the importance of the relationship between oral and systemic health, and advance the understanding of oral-systemic science and its appropriate integration into the clinical practice of mainstream dentistry and medicine by providing editorial that:

• Compels members of the dental and medical communities to embrace the growing body of science called oral-systemic medicine and accept the uncertainty of its ongoing evolution.

• Translates/transfers credible and relevant scientific findings and scholarly thought related to oral-systemic medicine into authoritative editorial that is educational and engages all sectors of the health-care professions (i.e., physicians and nurses, dentists and hygienists and allied health-care providers).

• Stimulates collaboration and innovative thinking on how to transcend professional boundaries to integrate clinical protocols that include application of oral-systemic medicine in everyday patient care.

Policy on Submission of Manuscripts: The opportunity to contribute to the editorial mission of Grand Rounds in Oral-Systemic Medicine^™ is offered to author candidates by honorary invitation. As such, unsolicited manuscripts are generally not accepted. Manuscripts published in Grand Rounds in Oral-Systemic Medicine^™ are written by authors who are invited to contribute to this body of knowledge based upon their academic, research or clinical expertise, from both dentistry and medicine, in specific subject matters that pertain to oral-systemic medicine.